| 학회 |
한국공업화학회 |
| 학술대회 |
2007년 가을 (11/02 ~ 11/03, 한경대학교) |
| 권호 |
11권 2호 |
| 발표분야 |
생물공학 |
| 제목 |
Fluorescence Detection for Protoporphyrin IX induced from 5-ALA and ALA-methyl ester in Incubated Liver Cancer Cells |
| 초록 |
To clarify the usefulness of fluorescent diagnosis for cancer, we investigated the optimal method of administrating 5-aminolevulinic acid(5-ALA), 5-aminolevulinic acid methyl ester(ALA-methyl ester) by analyzing fluorescence signal of Protoporphyrin IX(PpIX) in the cultured cells. 5-ALA and ALA-methyl ester were injected as a photosensitizer to the cancer liver cells(HepG2) and normal liver cells(Chang). Chang and HepG2 were incubated with various concentrations of 5-ALA and ALA-methyl ester(0-800 μg/mL). The cell viability was measured by MTT assay. |
| 저자 |
김명화, 윤선광, 이창섭
|
| 소속 |
계명대 |
| 키워드 |
5-aminolevulinic acid; 5-aminolevulinic acid methyl ester; Protoporphyrin IX
|
| E-Mail |
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