| 초록 |
Non-specific adsorption of protein on biomedical equipments, which are used for therapeutic and diagnosis purpose, can cause infection, blood coagulation, and sensitivity degradation. Lots of researches on antifouling coatings have been proceeded to solve these problems, however, researches on the mechanism were still elusive. In this study, we hypothesized that non-specific adsorption would be affected by surface energy. Polymers using oligo(Ethylene glycol)methacrylate, Hydroxyethlymethacrylate, 2-(dimethlyamino)ethlymetacrylate and (3-methamethaacryloylamino)propyl-dimethyl (3-sulfopropyl) ammonium hydroxide, 3-sulfopropyl methacrylate potassium monomers were introduced to silicon metal surface by using Surface Initiated Activator Regenerated by Electron Transfer Atom Transfer Radical Polymerization (SI ARGET ATRP). The correlation between surface energies of the polymer-coated surfaces and antifouling effect has been investigated through an enzyme-linked immunosorbent assay. |
