| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관) |
| 권호 |
34권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Releasebehaviors of dual drug eluting stents coated by using electrospray for anti-restenosis |
| 초록 |
In this study, biodegradable poly(lactide-co-glycolide) (PLGA) and poly(L-lactide) (PLLA) were used as a drug carrier for alpha lipoic acid-loaded stents. A drug eluting stent (DES) made of Cobalt-Chrome (Co-Cr) is used to open up any blocked ducts in human body. The development of coronary artery stenting can reduce the coronary occlusion and restenosis. Electrospraycoating system was utilized to coat biodegradable PLGA and PLLA containing drug on stent sample. Drug from DES sample was released in PBS (pH 7.4) at 37 ℃. The sample was then analyzed using UV-spectrophotometer for drug release concentration. The less polymer concentration, the faster drug release. |
| 저자 |
김동민1, 박철호1, 박귀덕1, 강종희1, 손태일2, 한동근1
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| 소속 |
1한국과학기술(연), 2중앙대 |
| 키워드 |
Drug eluting stent; Electrocoating; PLGA; PLLA; re-adsorption
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| E-Mail |
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