| 학회 | 한국공업화학회 |
| 학술대회 | 2013년 가을 (10/30 ~ 11/01, 대전컨벤션센터) |
| 권호 | 17권 2호 |
| 발표분야 | 포스터-정밀화학 |
| 제목 | Application of Organoaluminum reagents in the Synthesis of Amidines and α,β-Alkynyl Ketones |
| 초록 | So far, many organoaluminum reagents have proven as remarkable reagents in organic synthesis due to their inherent reactivity, wide range of applicability, low cost and commercial availability. Organoaluminum compounds can easily react with various heteroatoms in organic molecules, particularly with oxygen and nitrogen, even with carbon to form a strong coordinate complex (1:1). As a part of ongoing research on solid-phase synthesis of small organic molecules, we have extensively utilized dimethylaluminum-amide reagents introduce further diversity on to core scaffolds. In addition, we have developed new procedure for the synthesis of alkyl- or aryl-substituted amidines using nitriles and dimethylaluminum-amide reagents. Above results prompted us to investigate the addition reactions of alkynyldimethylaluminums onto nitriles and here our findings concerning the synthesis of α,β-alkynyl ketones are described. |
| 저자 | Korbad Balaji L., 이상협 |
| 소속 | 대구가톨릭대 |
| 키워드 | trimethylaluminum; nitriles; alkynes |
