| 학회 | 한국고분자학회 |
| 학술대회 | 2005년 가을 (10/13 ~ 10/14, 제주 ICC) |
| 권호 | 30권 2호 |
| 발표분야 | 고분자 합성 |
| 제목 | Phase behavior study of Star ‘Polymer-block-polypeptide’ synthesized by Combining Atom Transfer Radical Polymerization and Ring Opening Living Polymerization of α-Aminoacid-N-Carboxyanhydrides |
| 초록 | The synthesis and self organization of a novel class of triarm star shaped polymer–peptide block co-polymer by the combination of atom transfer radical polymerization and living ring opening polymerization of α-aminoacid-N-carboxyanhydride were studied extensively. This novel two-step strategy allows the incorporation of polypeptides into usual synthetic polymers. Triarm polystyrene with bromine at the chain ends was synthesized and the end bromines were converted to a macro initiator for the growth of poly-γ-benzyl-L-glutamate using an amido-amidate nickelacyle intermediate. This method allows an easy way for the preparation of a wide range of polymer-peptide architectures with control over polypeptide chain length avoiding the formation of homopolypeptide contaminants. The self assembly and phase behavior of these polymers were studies using X-ray diffraction, Variable temperature IR, DSC, TGA etc. Significant changes in nano and microstructure of the polymers were observed which depends on the block length and architecture of the polymer molecules. figure 1 |
| 저자 | 시노즈, 하창식, 김일 |
| 소속 | 부산대 |
| 키워드 | atrp; block copolymer; polypeptide; romp |
