| 학회 |
한국고분자학회 |
| 학술대회 |
2018년 봄 (04/04 ~ 04/06, 대전컨벤션센터) |
| 권호 |
43권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 I |
| 제목 |
A crosslinked ionic polymer thin film for infection-resistant and biocompatible medical application |
| 초록 |
The quest to fabricate new antibacterial surfaces has become a primary strategy to prevent device-associated infections (DAI). Herein, we propose a new strategy for anti-infective surfaces made of a cross-linked ionic polymer film. A initiated chemical vapor deposition (iCVD) process could generate a cross-linked ionic polymer film from 4-vinylbenzyl chloride (VBC) and 2-(dimethylamino) ethyl methacrylate (DMAEMA) monomers in vapor phase. The ionic polymer-deposited surfaces supported the healthy growth of mammalian cells while selectively inhibited the bacterial growth in co-culture models without any detectable cytotoxicity. Thus, the cross-linked ionic polymer-based antibacterial surface developed in this study can serve as an ideal platform for biomedical application requiring highly sterile environment. |
| 저자 |
최고로, 임성갑
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| 소속 |
한국과학기술원 |
| 키워드 |
Antibacterial coating; initiated chemical vapor deposition (iCVD); crosslinking; ionic polymer; biocompatibility.
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| E-Mail |
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