화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션)
권호 20권 1호
발표분야 생체재료_포스터
제목 Radiopaque and biodegradable polydioxanone stent for esophageal obstruction treatment
초록 In this study, biodegradable polydioxanone (PDO) stents were coated with hyaluronic acid-dopamine conjugate (HA-DA) and barium sulfate (BaSO4) to promote biocompatibility, tissue adhesiveness, and radiopacity for the treatment of esophageal obstruction. The amount of HA-DA on a surface was quantified with micro BCA assay. The radiopacity of PDO stent coated with BaSO4 was confirmed by X-ray. Tissue adhesiveness, degradation behavior, thermo-mechanical properties, and cyto-compatibility were evaluated in accordance with ISO and ASTM standards. Obtained results demonstrated that the PDO stent coated with HA-DA and BaSO4 might be a biocompatible stent with radiopaque and biodegradation.
저자 최슬기1, 이유진1, 안동준2, 한동근1, 정윤기1
소속 1한국과학기술(연), 2고려대
키워드 PDO; HA-DA; BaSO4; radiopaque
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