초록 |
The development of molecular chemo sensors/probes for the efficient and selective detection of physiologically and environmentally important toxic heavy metal ions and anions has attracted considerable attention over past few decades. The bioaccumulation of mercury ions throughout the food chain in the form of dangerous methylmercury species (CH3HgX) by certain anaerobic bacteria affects the nervous system and leads to severe diseases. Similarly, fluoride ions play a key role in a wide range of biological, medical and chemical processes, such as dental care, osteoporosis treatment and even in chemical warfare agents. On the other hand, extreme levels of fluoride ions in drinking water can cause severe diseases including dental and skeletal fluorosis, osteosarcoma, and can also lead to nephrotoxic changes and urolithiasis in humans. Therefore, it is important to design new molecular probes for the rapid, efficient and selective sensing of mercury and fluoride ions. |