| 학회 |
한국공업화학회 |
| 학술대회 |
2015년 봄 (04/29 ~ 05/01, BEXCO (부산)) |
| 권호 |
19권 1호 |
| 발표분야 |
생물공학_포스터 |
| 제목 |
Prospects of genetic engineered Shewanella oneidensis MR-1 for the production of 3-hydroxy propionic acid and its potential in Bioelectrochemical System |
| 초록 |
Internal redox imbalance, which is caused due to undisposed electrons, leading to high byproduct production, less conversion yield and eventually increase the final purification cost of process, is a major hurdle in biological production of platform chemicals. Here we employed genetic engineered Shewanella oneidensis MR-1 and demonstrated the controlling of intracellular NADH/NAD+ redox balance without affecting the production in batch cultures. S. oneidensis MR-1 can intrinsically transfer electrons directly to terminal electron acceptors (TEA) through a process called extracellular electron transfer (EET). We showed the prospects of biological production of 3-HP by a recombinant S. oneidensis MR-1 dhaB gdrAB KGSADH strain grown in a conical flask as a batch culture with chemical mediators and TEA and its prospect in Electrochemical Bioreactor Array (EBA). |
| 저자 |
김중래, Ganapathiraman Munussami, Somasundar Ashok, 송영은, 이선구, 박성훈
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| 소속 |
부산대 |
| 키워드 |
bioelectrochemcial system; biorefinery; platform chemicals
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| E-Mail |
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