| 학회 |
한국화학공학회 |
| 학술대회 |
2015년 봄 (04/22 ~ 04/24, 제주 ICC) |
| 권호 |
21권 1호, p.450 |
| 발표분야 |
생물화공 |
| 제목 |
Engineering Shewanella oneidensis MR-1 for the production of 3-hydroxy propionic acid and its prospect in Bioelectrochemical System |
| 초록 |
Biological production of platform chemicals from sustainable feedstock has been the central interest for alternative conventional chemical refinery process as well as an important attribute in developing clean technology. Internal redox imbalance is one of the bottleneck in biological production. We demonstrated the controlling of intracellular NADH/NAD+ redox balance using chemical mediators and terminal electron acceptors (TEA). Shewanella oneidensis MR-1, an electrochemically active bacterium can be employed to regulate redox imbalance. S. oneidensis MR-1 can intrinsically transfer electrons directly to electrodes through a process called extracellular electron transfer (EET) there by regulating internal redox status of the cells. In this study, we demonstrated the prospects of biological production of 3-HP by a recombinant S. oneidensis MR-1dhaB gdrAB KGSADH strain with chemical mediators and TEA. The production of 3-HP proved a promising aspect to proceed further with Electrochemical Bioreactor Array (EBA). |
| 저자 |
김중래, Ganapathiraman Munussami, Somasundar Ashok, 송영은, 이선구, 박성훈
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| 소속 |
부산대 |
| 키워드 |
bioelectrochemcial system; biorefinery; platform chemicals
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| E-Mail |
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| 원문파일 |
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