| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 가을 (10/07 ~ 10/08, 대구 EXCO) |
| 권호 |
35권 2호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Biohybrid Materials with Clustered Silver Nanoparticles for Surface Enhanced Raman Scattering Based Bioimaging |
| 초록 |
Surface Enhanced Raman Scattering (SERS) has been of interest for development of biosensors and bioimaging tools. Specifically, aggregates of Ag and Au nanoparticles produce SERS signal many orders higher than single nanoparticles. We have developed biohybrid materials having clustered silver nanoparticles with Raman labels as well as cancer targeting moieties for SERS-based bioimaging. Raman labels induced aggregation of single silver nanoparticles producing silver nanoclusters, encapsulated in poly(acrylamide-co-acrylic acid)s by electrohydrodynamic jetting. A variety of cancer targeting moieties can be introduced to produce biohybrid materials. The silver nanoclusters in biohybrid materials have controllable SERS sensitivity depending on their density as well as higher chemical stability, biocompatibility and reproducibility as compared to the bare silver nanoclusters. The biohybrid materials with the silver nanoclusters can have a potential for advanced SERS-based bioimaging. |
| 저자 |
굴람자라니1, 정찬우2, 이상엽1, 주재범2, 임동우1
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| 소속 |
1한양대, 2생명나노공학과 |
| 키워드 |
Biohybrid Materials; Nanoparticles; Surface Enhanced Raman Scattering; Bioimaging
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| E-Mail |
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