| 학회 |
한국화학공학회 |
| 학술대회 |
2011년 봄 (04/27 ~ 04/29, 창원컨벤션센터) |
| 권호 |
17권 1호, p.418 |
| 발표분야 |
생물화공 |
| 제목 |
Surface Functionalization of a-C/ZnO Core-Shell Nanowires Based on Self-Assembled Monolayers for Biosensor Applications |
| 초록 |
We present the biomolecules immobilization on amorphous carbon (a-C)/Zinc Oxide (ZnO) core-shell nanowires (NWs) using NH3 plasma treatment and a self-assembled monolayer (SAM). NH3 plasma treatment was carried out in an Inductively Coupled Plasma (ICP) system in order to create amine group onto the surface of the a-C/ZnO core-shell NWs. For generation of SAMs, we employed an O2 plasma treatment method for the formation of hydroxyl group onto the surface of a-C/ ZnO/ core-shell NWs. Finally, the biomolecules such as anti-AFP antibody could be immobilized to the hydroxylated a-C/ZnO core-shell NWs via a terminal amine (NH2) functional group which linked with the assembled SAM layer formed by treatment with APTES and glutaraldehyde. Analysis of the functional groups on the surface of the a-C/ZnO core shell NWs was performed using Fourier Transform Infrared Spectroscopy (FT-IR). In this work, we demonstrate that antibodies bind covalently and non-covalently with and without SAM, respectively on the surface of a-C/ZnO core-shell NWs. |
| 저자 |
Deepti Sharma, 임연호, 김진태, Khan Mohammad Rizwan, 육영근, 구아영, 서지혜
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| 소속 |
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