| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 봄 (04/12 ~ 04/13, 대전컨벤션센터) |
| 권호 |
37권 1호 |
| 발표분야 |
의료용고분자 부문위원회 |
| 제목 |
Preparation and Characterization of Rapamycin incorporated drug delivery carrier |
| 초록 |
Rapamycin, also known as sirolimus, is an inexpensive immunosuppressive drug that has been well-studied in renal transplantation and in drug-eluting stents as an antiinflammatory/anti-proliferation agent. In this study, Carboxymethyl chitosan-graft-poly(ethylene glycol)-graft-Cholesterol(OCMPEGChol) was synthesized with carboxymethyl group modified Chitosan and methoxy poly(ethylene glycol) by chemical reaction for Rapamycin(Rapa) delively system. The structure were investigated by fourier transform infrared FT-IR(Fourier transform infrared), 1H-NMR(1Proton Nuclear Magnetic Resonance). Also, particle size and particle image were measured by DLS(Dynamic Light Scattering) and TEM(Transmission electron microscopy). These results to expected to shape core shell type nanoparticle. |
| 저자 |
이경재, 김영민, 남정표, 박준규, 김원석, 최창용, 김명렬, 장미경, 나재운
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| 소속 |
순천대 |
| 키워드 |
Carboxylation chitosan; Rapamycin; Sirolimus; DDS; .
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| E-Mail |
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