초록 |
The research goal of my lab is to identify the underlying mechanisms by which cells and tissues interact with polymeric matrix so we can apply this knowledge to develop the next generation of polymeric biomaterials. In this context, microscale technologies are emerging as powerful tools for controlling the interaction between cells and their surroundings for biological studies, tissue engineering, and cell-based screening. In addition, hydrogel biomaterials have been increasingly used in various translational applications since they provide cells with a hydrated 3D microenvironment that mimics the native extracellular matrix. In recent years, various approaches have been developed by merging microscale techniques with biomaterials for directing stem cell differentiation and generating complex 3D tissue-like constructs. In this talk, I will describe the fabrication and the use of microscale techniques to engineer biocompatible biomaterials to control cell-material and cell-cell interactions for translational research applications. |