| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO)) |
| 권호 |
23권 1호 |
| 발표분야 |
생물공학_포스터 |
| 제목 |
Monitoring of cell-cell interaction in a programmable static droplet array with a confined microenvironment |
| 초록 |
Cell-cell interaction can occur through biochemical signaling molecules, regulating a variety of biological responses such as quorum sensing, biofilm formation, and inflammatory response. However, traditional cell culture systems are difficult to accurately reproduce the effects of cell-cell interactions and mixed cell populations, have no single cell resolution, and often have limited sensitivity and accuracy. Thus, there is a growing need for a novel platform for isolating, manipulating, tracking, and imaging cells to better study the various cell-cell interaction scenarios. Here we present a programmable static droplet array (SDA) for monitoring of the effect of population on natural cell-cell contact and signaling processes in a confined microenvironment. The SDA provides a valuable research tool to study cell-cell communication and signaling in a controlled microenvironment with the sensitivity and accuracy required for screening and long-term phenotypic analysis. |
| 저자 |
김동영1, 진시형1, 이병진1, 정성근1, 이성식2, Matthias Peter2, 이창수1
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| 소속 |
1충남대, 2ETH Zürich |
| 키워드 |
static droplet array; microvalve; cell-cell interaction
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| E-Mail |
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