| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터) |
| 권호 |
36권 2호 |
| 발표분야 |
기능성고분자－막분리용 고분자 |
| 제목 |
Microfluidic Protein Detection Using a Novel Polyacrylic Acid block Liquid Crystalline Polymer |
| 초록 |
The interface between 5CB microdroplets and water decorated by an amphiphilic block copolymer of PAA-b-LCP was examined for protein detection. Two model proteins, Lysozyme and Bovine serum albumin (BSA) with isoelectric points of 11.1 and 4.9, respectively were selected for this study. The complex formation between the charged proteins and PAA block of the PAA-b-LCP at the aqueous-LC interface resulted in the change of the LC orientation in the droplet induced by spatial electrostatic interactions. The transition of the LC microdroplets from radial to bipolar can be easily visualized under crossed polarizers. This work demonstrates a simple approach for the development of a LC-based sensor for label-free detection of proteins, which may find diverse applications in biomedical field. |
| 저자 |
왈리울라, 박수영
|
| 소속 |
경북대 |
| 키워드 |
Microdroplets; 5CB; PAA-b-LC11P; Lysozyme; BSA
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| E-Mail |
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