| 학회 |
한국공업화학회 |
| 학술대회 |
2008년 가을 (11/12 ~ 11/14, ICC 제주) |
| 권호 |
12권 2호 |
| 발표분야 |
화학공정 |
| 제목 |
KINETIC STUDY OF AN ACTIVE PHARMACEUTICAL INGREDIENT IN BATCH CRYSTALLIZATION BY COOLING MODE |
| 초록 |
The crystallization kinetic of an active pharmaceutical ingredient (API) was investigated in cooling mode. The relationship between induction time and the supersaturation was obtained for understanding mechanism of nucleation. The nucleation mechanism including homogeneous and heterogeneous nucleation was grasped with respect to the supersaturation. From the results of nucleation experiments, the interfacial tension was determined. Furthermore, the kinetic of crystal growth was also obtained. |
| 저자 |
Nguyen Thi Nhat Phuong, 김광주
|
| 소속 |
한밭대 |
| 키워드 |
kinetic; nucleation; crystal growth; FBRM
|
| E-Mail |
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