화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2006년 가을 (10/27 ~ 10/28, 고려대학교)
권호 12권 2호, p.1620
발표분야 분리기술
제목 Separation of D-Psicose and D-Fructose Using Simulated Moving Bed
초록 D-psicose was approved rare sugar as the definition of The International Society of Rare Sugars. Generally, Rare sugars have much potential for medical purpose. Many functions of D-psicose were also reported such as immunosuppressant in allogeneic orthotopic liver translation in rats, potential inhibitors of various glycosidases, potential inhibitors in ischemia-reperfusion injury of the rat liver, and low-calorie sweetener.
D-psicose is epimerized from D-fructose by enzyme reaction. The enzymes, such as D-tagatose-3-epimerase and D-psicose-3-epimerase have been reported in several researches. Because these enzyme are necessary the specific pH condition for the optimal reaction, the several kinds of pH-buffer were used in almost researches.
In this study, several experiments to remove pH-buffer efficiently were performed. The frontal analysis were performed to estimate the isotherm parameters of D-psicose and D-fructose. The SMB process to purify D-psicose from D-fructose was designed and simulated using Aspen Chromatography.
저자 김진일1, 이주원1, 김정근2, 박영수1, 구윤모1
소속 1인하대, 2초정밀생물분리기술연구센터
키워드 rare sugar; psicose; fructose; SMB
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