| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 봄 (04/10 ~ 04/11, 컨벤션 뷰로(대전)) |
| 권호 |
33권 1호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Preparation and characterization of sponge using demineralized bone particle |
| 초록 |
One of the significant natural bioactive materials is demineralized bone particle (DBP) whose has a powerful inducer of new bone growth. Crosslinked DBP sponges were characterized for the possibility of tissue engineered scaffolds. DBP sponges were prepared by crosslinking with 1 ethyl-3-(3-dimethylaminpropyl) carbodiimide hydrochloride (EDC). DBP powders dissolved in 3% (v/v) acetic acid aqueous solution for 48 hrs and freeze dried. EDC solution (H2O: ethanol = 5: 95) with 1~100mM concentration for 24 hrs and lyophilized. DBP sponges were characterized by scanning electron microscopy and Fourier transforms infrared spectrometer and water absorption ability. Those results, It was observed that the concentration of EDC might be exceeded 50 mM to get good physical characteristics. In conclusion, it seems that DBP sponge cold be very useful for the applications of tissue construction. Acknowledgement: This work was supported by KMOHW (0405-BO01-0204-0006). |
| 저자 |
백미옥1, 김순희1, 소정원1, 임지예1, 홍현혜1, 정수현1, 최진희1, 이해방2, 강길선1
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| 소속 |
1전북대, 2한국화학(연) |
| 키워드 |
DBP sponge |
| E-Mail |
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