| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
Korea-Australia Joint Symposium: Next Generation Polymer Science and Technology (English) |
| 제목 |
Synthesis of Gradient Copolymers Based on One-pot Cationic Copolymerization of Aliphatic and Aromatic 2-Oxazolines |
| 초록 |
Gradient amphiphilic copolymers represent unique class of copolymers with the gradual monomers composition distribution along the polymer chain adopting similar self-assembly behavior as in the case of amphiphilic block copolymers. Poly(2-oxazolines) prepared via living cationic ring-opening polymerization (LCROP) have been recognized as promising biomaterials for different biomedical applications. Recently, gradient copolymers by LCROP of 2-ethyl-2-oxazoline and 2-(4-dodecyloxyphenyl)-2-oxazoline was used for the preparation of highly stable nanoparticle for encapsulation of curcumin. In this work, we present the synthesis of library of gradient copoly(2-oxazolines) with different aromatic 2-oxazolines and different copolymer composition. We investigated the effect of structure of hydrophobic monomer on the self-assembly behavior and drug-loading capacity of selected drugs. Acknowledgment: Authors are thankful SRDA for financial support in the projects SK-KR-18-0011 and APVV-15-0485. |
| 저자 |
Juraj Kronek1, Jiwon Jeong2, Zuzana Kroneková3, Shubhashis Datta1, Daniel Jancura4, Daewon Sohn5
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| 소속 |
1Polymer Institute of the Slovak Academy of Sciences, 2Department of Chemistry, 3Hangyang Univ., 4Center for Interdisciplinary Biosciences, 5Technology and Innovation Park |
| 키워드 |
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| E-Mail |
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