| 학회 | 한국공업화학회 |
| 학술대회 | 2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 | 26권 1호 |
| 발표분야 | 포스터-생체재료 |
| 제목 | Polymeric Microspheres including Magnesium Hydroxide and Anti-oxidant Agents for Functional Dermal Filler |
| 초록 | Polymeric microspheres containing magnesium hydroxide (MH) and antioxidants such as apocynin (APO) and astaxanthin (ATX) have been prepared as functional skin filler with enhanced physical chemistry and biological performance. In this study, the polycaprolactone (PCL) microspheres containing MH effectively neutralized acidic degradation products from polymer degradation. The microspheres comprising antioxidants were sustained released without initial burst release. In addition, the microspheres was displayed positive effects such as tissue regeneration and collagen production improvement in in vivo test. In conclusion, these results suggest that the prepared microspheres have great potential as a functional dermal filler for skin aesthetics and facial plastic surgery. Acknowledgments: This research was supported by Basic Science Research Program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education (2021R1I1A1A01045745). |
| 저자 | 허윤, 김다슬, 이세미, 한동근 |
| 소속 | 차의과학대 |
| 키워드 | Dermal filler; PCL microspheres; Magnesium hydroxide; Antioxidant; Astaxanthin |
