| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO)) |
| 권호 |
25권 1호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Hydrophilic surface modification of Poly-L-lactide (PLLA) microsphere for dermal filler application |
| 초록 |
PLLA is a synthetic biodegradable polymer which can be naturally degraded in human body. Such property makes PLLA useful for applications in dermal fillers, where the injected material requires to be safely removed without any surgical incision. Despite of its advantages, it’s relatively hydrophobic surface makes cell adhesion difficult and hinder attachment of macrophage and fibroblasts, which are crucial cells that play important role in collagen regeneration. In this study, PLLA microsphere was treated with plasma for surface treatment in order to increase hydrophilicity of the PLLA microsphere. For surface modification, a new dielectric barrier discharge (DBD) type plasma device, and specific conditions such as the type of gas, power applied, pressure, and flow rate were varied to optimize plasma treatment effect. We hope that plasma surface modification technique opens up new possibility in this area. |
| 저자 |
이청천1, 곽민석1, 한정우1, Lia Priscilla1, 함정율1, 권한진1, 김진영2, 양동훈2, 김상섭2
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| 소속 |
1(주)울트라브이, 2인하대 |
| 키워드 |
Plasma treatment; surface modification; PLLA; microsphere; microparticle; dielectric barrier discharge; dermal filler
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| E-Mail |
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