| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터) |
| 권호 |
40권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Synthesis and Evaluation of MPEG-Polyester Block copolymer with functional group |
| 초록 |
MPEG-b-PCL as a thermo-responsive polymer holds great promise in biomedical applications. However, MPEG-b-PCL has not functional group with side chain, and thereby limited to application. Overcome this problem, we introduced functional group in PCL backbone to enhance facilitate a variety of applications. We synthesized of amphiphilic MPEG-b-PCL based-block copolymers bearing functional side groups on the PCL block by ring-opening polymerization. The thermal properties (Tg and Tm) of the block copolymers depend on the functional pendant group on PfCL composition. The derivatized MPEG-b-(PCL-co-PfCL) di-block copolymer solutions exhibited sol-to-gel phase transitions upon a temperature increase. The sol-to-gel phase transition depended on both the type of functional group on the PfCL and the PfCL content in the PCL segment. These results indicate that MPEG-b-(PCL-co-PfCL) di-block copolymer solutions may potentially be used as thermo-responsive in situ gel-forming systems. |
| 저자 |
이보근, 권두연, 권진선, 박지훈, 김재호, 김문석
|
| 소속 |
아주대 |
| 키워드 |
PCL; Thermo-responsive; Hydrogel; Functional group; Polyester
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| E-Mail |
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