| 초록 |
Contact lens is especially noticeable for healthcare applications because it can be used as an efficient interface between a human body and the electronic device. Here, we developed a smart contact lens system for theranosis of diabetic retinopathy as a model for wirelessly powered healthcare systems. The smart contact lens system was composed of four miniaturized components: real-time electrochemical biosensor, self-regulated pulsatile drug delivery system, wireless power transfer system by resonant inductive coupling, and complementary metal–oxide-semiconductor integrated circuit-based microcontroller chip. Connected with a commercially available wireless communication electronic device, tear glucose level was measured as a non-invasive alternative to conventional blood glucose tests. Furthermore, we successfully demonstrated the controlled pulsatile drug delivery from gold coated reservoirs integrated within the remotely powered lens for various ocular theranostic applications. |
