| 초록 |
The purification efficiency of (+)-dihydromyricetin, a bioactive plant flavonoid, was remarkably improved through ultrasound-negative fractional precipitation. Precipitation efficiency has been dramatically improved, and the time required for precipitation has been reduced compared to conventional methods. As a result of investigating the mechanism of fractional precipitation in which ultrasonic cavitation and negative pressure cavitation bubbles were introduced, it was found that the bubble itself contributes to the improvement of precipitation efficiency. In addition, the ultrasound-negative pressure cavitation precipitation behavior was quantitatively investigated by calculating the precipitate size and diffusion coefficient of (+)-dihydromyricetin. [This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Government of Korea (MSIT) (Grant Number: 2021R1A2C1003186).] |
