| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 가을 (10/07 ~ 10/08, 대구 EXCO) |
| 권호 |
35권 2호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Development of a porous elastic scaffold using supercritical CO2 foaming technique for cartilage tissue engineering |
| 초록 |
Supercritical carbon dioxide (SCCO2) is attractive, because its critical temperature and pressure values are relatively low. Poly(L-lactide-co-ε-caprolactone (PLCL) is a biodegradable polymer with elastic properties. It has been used in the development of scaffolds for cartilage tissue engineering. Usually, organic solvents such as chloroform or dichloromethane are used for the fabrication of a PLCL scaffold through conventional methods. This leads to a cytotoxic effect and a long processing time. In order to alleviate these problems, a supercritical fluid foaming technique is introduced here. In this study, we investigated the effects of pressure, temperature, and depressurization rate on the PLCL foaming. Further, scaffolds were evaluated by various tests. From the results, we confirmed that our scaffolds had the ability to function as scaffolds for cartilage tissue engineering |
| 저자 |
김수희1, 정영미1, 김상헌1, 홍정호2, 김수현1
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| 소속 |
1한국과학기술(연), 2고려대 |
| 키워드 |
cartilage tissue engineering; PLCL; supercritical fluid
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| E-Mail |
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