| 초록 |
Poly(lactide-co-glycolide) (PLGA) polymer chains were directly grafted onto the surface hydroxyl groups of hydroxyapatite (HA) to observe the effects of HA surface modification on the interfacial adhesion, and thus the properties, of PLGA/PLGA-g-HA composites. FTIR analysis indicated ester linkage formation at the HA surface, with the grafted polymer content of 10.032 wt%. Solid-state 1H NMR spectra indicated that the amount of HA surface hydroxyl groups decreased by 3.125%. Molecular weight reduction was measured by GPC. XRD patterns and FESEM micrographs further verified successful grafting. After grafting, PLGA/PLGA-g-HA composites were prepared via three different blending methods. The properties of the composites were determined by differential scanning calorimetry, tensile testing, and dynamic mechanical analysis. The results show that the preparation method has important effects on the properties of the final PLGA/PLGA-g-HA composite. |
