화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2021년 가을 (11/03 ~ 11/05, 대구 엑스코(EXCO))
권호 25권 2호
발표분야 포스터-생체재료
제목 A Biomimetic Fluorescent Probe Based On Fluorescein for Bioimaging Applications
초록 Bioimaging technology that uses fluorescence probe has recently received much interest for the detection, visualization and characterization of the biological processes at the molecular level. We report here three fluorescent probe (UU-F, SS-F, and US-F) based on the combination of fluorescein with lipophilic groups that consist of saturated (S) and unsaturated (U) C-18 fatty acid. Live cell experiments performed on canine adipose-derived mesenchymal stem cells demonstrated that all three compounds well localized in cellular membrane, confirmed by CLSM. In particular, US-F showed good uptake, confirmed by FACS.
저자 문형규, Turpu Sheshashena Reddy, 정회빈, 최명석
소속 건국대
키워드 Fluorescein; Fluorophore; Bioimaging; Cell membrane
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