화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU))
권호 23권 2호
발표분야 포스터_생체재료
제목 Synergistic combination of zwitterionic and tetra-fluorinated groups for anti-thrombotic polymer additives
초록 To improve sufficient antifouling properties, zwitterionic materials have been proposed as new generation materials to inhibit protein adsorption and formation of biofilm. Moreover, many studies have demonstrated that fluorinated materials have antifouling and antimicrobial effects. Here, we designed novel zwitterionic and tetra-fluorinated polyurethane (ZFPU) additives to confer anti-fouling and anti-thrombotiic effects and blended these with polyvinyl chloride (PVC). 1HNMR and FTIR analyses showed that the zwitterionic groups and fluorinated groups were successfully introduced onto the ZFPU backbone. We also investigated the protein adsorption, platelet adhesion and wettability of additives-blended PVC films. Our results demonstrated that the ZFPU additives-blended PVC surfaces significantly suppressed protein adsorption and platelet adhesion than those of pristine PVC surface.
저자 강종희, 최수연, 임충만, 정윤기
소속 한국과학기술(연)
키워드 anti-thrombotic polymer
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