| 초록 |
Polymers with sol-gel transition temperature near room temperature and high bio-compatibility have attracted much attention in biomedical field. In this study, thermo-responsive ABA triblock copolymers were synthesized by anionic ring-opening polymerization, including poly(ethylene oxide) as the B block and thermo-responsive random copolymer of isopropyl glycidyl ether and ethyl glycidyl ether as the A block. Transition temperature of A block was controlled by the ratio of the two monomers. As the polymer concentration increases, hydrogel was formed above gel temperature, that decreases as the concentration of polymer or hydrophobicity of A block increases. Here, the gel relaxation time of the hydrogels at various polymer concentrations and various temperature was measured by rheometer with the help of time-Temperature Superposition (tTS) principle. We found that with a small change of the hydrophobicity in A block, the relaxation time is dramatically changed. |
