| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션) |
| 권호 |
20권 1호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Gelatin/Itaconic acid Nanoparticles Preparation by Nanoprecipitation for Biomedical Applications |
| 초록 |
Natural polymer based nanoparticles have been used for various biomedical applications such as drug/gene delivery, tissue engineering, and pharmaceutical formulation due to their excellent biocompatibility and biodegradability. In this study, gelatin/itaconic acid nanoparticles with 80-200 nm were produced by nanoprecipitation technique. Ethylcabodiimide was used as a carboxyl activating agent for the coupling of primary amines to yield amide bonds. We have also done the surface modification with poly-L-lysine for the purpose of surface charge controls on the surface. Physicochemical characterization with FT-IR, SEM, and swelling test demonstrated that the inclusion of itaconic acid in the particles could increase their water content by 2.2-folds and the surface modification with poly-L-lysine change the surface charge from approximately -20 to +10. |
| 저자 |
Phornsawat Baipaywad, Penphitcha Amonpattaratkit, 박한수
|
| 소속 |
중앙대 |
| 키워드 |
Gelatin nanoparticles; Nanoprecipitation; Biomedical; Biocompatibility; Swelling
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| E-Mail |
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