초록 |
Bioabsorbable membrane was prepared using gellan gum (GEL)-glycol chitosan (GC) containing bone graft materials(BGM) for guided bone regeneration (GBR). The GEL/GC membrane was characterized by Fourier transform infrared (FTIR), degradation, contact angle, tensile strength and cell viability. The result showed that by increasing the BGM content in GEL/GC membrane, the degradable and mechanical properties was decreased. New bone was observed through micro-CT and histological evaluation of forming a defect in rat calvarial and fixing the membrane. The amount of newbone regeneration was significantly greater in GEL/GC-BGM group than the GEL/GG membrane. The GEL/GC membrane blocked the soft tissue and has effects on the new bone formation. |