| 초록 |
With a rapid progress in DNA nanotechnology, DNA-based nanostructures have attracted considerable attention in biomedical applications due to high bicompatiability, prescisely controlled sizes and shapes, and facile preparation. This talk will introduce a promising platform of a well-defined Y-shaped DNA nanostructures to use a gene carrier itself and to form polymeric nanoparticles with a low-molecular weight cationic carrier for an efficient siRNA-mediated gene silencing in cancer cells as well as to use molecular probe for highly sensitive and rapid detection of specific DNA and proteins. |
