초록 |
For application of surface enhanced Raman scattering (SERS) in various field of research, developing sensitive, stable,and reproducible plasmonic substrate is a major issue for many researchers. For this purpose, biotemplates draw interests due to their predictable and/or designable structures in nanoscale. In this work,bacteriophage MS2 was used as a template for making highly-ordered assembly of gold nanoparticles into a plasmonic 'nanoraspberry' structure. Surface lysine groups were functionalized with linker to regularly orient the gold nanoparticles, which makes reproducible plasmon coupling effect and hence SERS signal enhancement. The influence of ordered assembly of gold nanoparticle was predicted by the electromagnetic simulation and confirmed with the actual measurement of SERS enhancement effect. The sensitivity and reproducibility of SERS signal enhanced from nanohalo structure were confirmed in this study by using rhodamine 6G as an analyte. |