| 초록 |
Recently, nano-sized graphene oxide (NGO) nanocomposites have attracted increasing attention for biomedical applications, such as drug delivery system, photothermal and photodynamic therapy of cancer. In particular, reduced graphene oxide (rGO) composites have an excellent photothermal conversion efficiency compared to normal GO composites. However, it is difficult to use in vivo experiments since GO tends to reduce the number of functional groups after reduction, resulting poor dispersibility in water. In this work, we prepared the gold nanorods (GNRs) combined with the surface- modified rGO, which can further improve the dispersibility and biocompatibility of rGO composites. In addition, Ce6 was attached on rGO and the photodynamic effect was also confirmed. The physicochemical properties, morphologies and optical properties of rGO-GNRs composites were determined. Their photothermal stabilities were also investigated upon exposure to near-infrared (NIR) light irradiation.
|
