화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2015년 봄 (04/22 ~ 04/24, 제주 ICC)
권호 21권 1호, p.449
발표분야 생물화공
제목 Silver-coated Gold Nanostar for Ultra-Sensitive SERS Nanoprobe
초록 Various types of SERS nanoprobes have been developed for ultra-sensitive biomolecular detections including in vitro and in vivo bioimaging. Here, we developed gold nanostar coated with silver shell (AuNS@Ag) as an ultra-sensitive SERS nanoprobe. We expected that AuNS@Ag has stronger SERS signals than AuNS without silver shell because the interface between gold nanostar and silver shell can make much more hot spots, and they can be applied to various multiplex biomolecular detections. Raman-active chemicals and several fluorescent dyes were captured on gold nanostar stabilized PVP and then they were covered with silver shell by hydroquinone reduction method to achieve the higher enhancement factor (EF). The improved SERS signals of AuNS@Ag was confined by confocal Raman Spectroscopy regarding the feasibility of multiplexing bioassays or bioimagings.
저자 유지인, 이슬비, 이상명
소속 강원대
키워드 SERS; gold nanostar; silver shell; multiplex SERS probe
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