| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 봄 (04/10 ~ 04/11, 컨벤션 뷰로(대전)) |
| 권호 |
33권 1호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Behavior of human bone marrow derived mesenchymal stem cells on different wettable surfaces. |
| 초록 |
The effect of surface wettability in the view of the cell-surface interaction has been extensively studied because of its importance in the design of implant scaffolds. Therefore, the cell-surface interaction is one of the most important factors in the development of implantable scaffolds. In our study, Corona discharge treatment was applied to modify the surface of polyethylene(PE). The wettability of PE surface was gradually increased by power increase of a corona treatment along the PE length, indicating that the hydrophilicity of PE surface increased gradually. The adhesion and proliferation behavior of human bone marrow derived mesenchymal stem cells (hBMSCs) on the gradient PE surface was evaluated. We found that hBMSCs were adhered to and proliferated on better highly hydrophilic than hydrophobic surfaces. These results indicate that surface wettability plays an important role in the cell attachment and proliferation. |
| 저자 |
이주영1, 안현희1, 김병수1, 김경숙1, 이정화1, 김문석1, 이봉2, 강길선3, 이해방1
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| 소속 |
1한국화학(연), 2부경대, 3전북대 |
| 키워드 |
polyethylene; hBMSC; wettability; hydrophilicity; hydrophobicity
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| E-Mail |
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