화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2008년 가을 (10/23 ~ 10/24, 부산 BEXCO)
권호 14권 2호, p.2756
발표분야 생물화공
제목 Construction and Comparative Analysis of Two-Component System and Metabolic Network Profile based Phylogenetic trees
초록 In this paper, two-component system gene profile and metabolic network gene profile based phylogenetic trees were constructed, and two trees were compared with each other to estimate the evolutionary relation of bacterial sensing system and metabolism. Gene profiles of TCS and metabolic network suggested that bacteria employed different evolution strategies for optimization of two-component system and metabolic network. Via comparative analysis it was found that TCS based tree showed better family grouping than metabolic network based tree, and this result deduced that TCS and metabolic network have been modified following self-evolution and recruitment models, respectively.
[This work was supported by the Korean Systems Biology Program from the Ministry of Education, Science and Technology through the Korea Science and Engineering Foundation (No. M10503020001-07N0302-00112)]
저자 정 민, Thuy Vu An Nguyen, 홍순호
소속 울산대
키워드 Two-Component System; Metabolic Network; Phylogenetic tree
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