| 초록 |
Recently, atomic force microscope (AFM) has been potentially applied to characterizing the physical properties of bio- and nano-materials with extremely high resolution. The biophysical application of AFM includes bio-imaging, measuring of inter- and intra-molecular interactions, force mapping on living cells, and characterizing bio-compatible materials. Our research is focused on imaging proteins selectively attached on a gold dot array and pico-level measuring of interactions between biomaterials, such as streptavidins, biotins, and antibodies using AFM. To measure the interaction between biomolecules, AFM tips were modified with biotins and antibodies and then approached to the proteins-modified gold dots. On the other hand, we discuss about the mechanical properties of bio-compatible polymer nanofibers with the diameters ranging from several tens of nm to about 200 nm. |
