| 학회 | 한국공업화학회 |
| 학술대회 | 2014년 봄 (04/30 ~ 05/02, 제주국제컨벤션센터) |
| 권호 | 18권 1호 |
| 발표분야 | 포스터-무기재료 |
| 제목 | Synthesis of biocompatible hollow metal-organic frameworks capsules for improved enzymatic response |
| 초록 | Metal–organic frameworks (MOF) are crystalline porous materials consisting of metal ions coordinated by organic ligands. Recently, Cu3BTC2 MOF hollow capsules have been reported by interfacial synthesis method using immiscible two liquid phase in a microfluidics system. However, this system has not being applied to biomaterials yet; using MOFs prepared by biocompatible ligands (bio-MOFs) important breakthroughs are expected. The non-toxic bio-MOFs (e.g. iron fumarate MIL-88A) are of crucial interest for applications such as controlled release of drugs, imaging or enzyme catalytic reaction. Nevertheless, enzyme can be easily degraded and a protective porous shell would be beneficial to improve the bioactivity. Herein, we developed the new functional hollowed MOF capsules using microfluidics system. Several types of enzymes were chosen for further biomass related applications. These enzymes were encapsulated and protected by defect-free MOF capsules. |
| 저자 | 정관영, 김동표 |
| 소속 | 포항공과대 |
| 키워드 | Metal-organic frameworks; enzyme; hollow capsule |
