| 학회 | 한국재료학회 |
| 학술대회 | 2017년 봄 (05/17 ~ 05/19, 목포 현대호텔) |
| 권호 | 23권 1호 |
| 발표분야 | B. 나노화학/바이오 분과 |
| 제목 | Preparation of alginate/nano-hydroxyapatite microsphere for bone tissue regeneration |
| 초록 | We designed alginate/nano-hydroxyapatite hybrid microsphere for bone tissue regeneration. First, we prepared alginate/nano-hydroxyapatite bead with micro scale and then post-treated. The size of sintered microsphere was easily regulated by alginate/nano-hydroxyapatite combination ratio. The morphology and structural composition of microsphere was investigated by scanning electron microscopy (SEM), X-ray diffraction (XRD), Energy-dispersive X-ray spectroscopy (EDX), Brunauer–Emmett–Teller (BET) and mercury porosimetry analysis. In addition, we investigated bone inductive protein loading capability and release behavior from the microsphere sustainedly. We also demonstrated osteoblast adhesion, proliferation and differentiation due to released osteogenic inductive protein from the microsphere. This microsphere might be utilized for bone substitute materials and bone tissue engineering approaches. This work was supported by NST grant by Korea Government (MSIP) (No CAP-15-09-KIMS) |
| 저자 | Honghyun Park, Kyubin Byun, Hui-suk Yun |
| 소속 | Korea Institute of Materials Science (KIMS) |
| 키워드 | <P>alginate; nano-hydroxyapatite; microsphere; bone; tissue regeneration</P> |
