초록 |
Hydrogels have been used as biocompatible material platforms for tissue regeneration and drug delivery as it can hold a large amount of water within its three-dimensional hydrophilic polymer network. However, due to high amount of water, most hydrogels show limited mechanical properties and do not exhibit adequate adhesiveness to tissue; it is challenging to achieve adhesive hydrogels with high mechanical properties. Increasing adhesion to tissue by incorporation of adhesive moieties in polymer chain often leads to the decrease in the strength of hydrogel, resulting in a limited application of adhesive hydrogels. In this talk, I will introduce our recent achievements for fabricating adhesive hydrogels with enhanced adhesiveness by increasing the strength of hydrogel and the adhesion to tissue simultaneously, which may be potentially applicable to soft tissues mimetics and transdermal drug delivery. |