화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU))
권호 19권 2호
발표분야 콜로이드계면화학_포스터
제목 In situ self-assembly of collagen fibers integrated with a hydrophobically-modified 3D networked microporous gel
초록 There is increasing evidence that matrix stiffness and permeability modulates various phenotypic activities of cells surrounded by three-dimensional (3D) matrix in native tissue. Therefore, we hypothesized that a collagen assembled with the improved structural integrity in dermis layer would regulate dermal fibroblasts activities to remodel, repair, and recreate skin dermis. This study examines the effects of hydrophobically-modified 3D networked microporous gel on enhancing the structural integrity of the collagen assembly and further regulating the morphology, growth rates, and glycosaminoglycan (GAG) production of dermal fibroblasts.
저자 정재현1, 이해광2, 이성훈2, 민대진2, 김희진1, 임준우1
소속 1숭실대, 2AmorePacific
키워드 Collagen; Fibroblast; Skin; Hydrophobically-modified; Hydrogel
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