화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2006년 가을 (11/10 ~ 11/11, 경희대학교(수원캠퍼스))
권호 10권 2호
발표분야 생물공학
제목 Biotransformation of Daidzein to 7,6,4’-trihydroxyisoflavone and 7,3',4’-trihydroxyisoflavone.
초록 The soy isoflavones are naturally occurring compounds which exhibit estrogen-like function . Diadzein which showed the highest content in Doenjang was hydroxylated to form mono-hydroxylated isoflavones. Using bacterial species screened from Doenjang, Daidzein was transformed to 7,6,4’-trihydroxyisoflavone. And also using Nocardia farcinica, Daidzein was transformed to 7,3’,4’-trihydroxyisoflavone. When hydroxylated, it was reported that hydroxylated isoflavones show higher anti-bacterial, anti-oxidative and anti-cancer activity. The product was identified using HPLC, GC-MS and MALDI-TOF.
저자 최권영, 김병기, 노창현, Bishnu Pandey, 김준형
소속 서울대
키워드 Isoflavone; Doenjang; Daidzein; Hydroxylation
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