초록 |
Understanding and controlling the function of the brain is a challenge in modern neuroscience. Optogenetics allows rapid, temporally specific control of neuronal activity by targeted expression and activation of light-sensitive proteins. Implementation typically requires remote light sources and fiber-optic delivery schemes that impose considerable physical constraints on natural behaviors. In this report we bypass these limitations using technologies that combine thin, mechanically soft neural interfaces with fully implantable, stretchable wireless radio power and control systems. The resulting devices achieve optogenetic modulation of the central and peripheral nervous system. Soft, thin devices are minimally invasive, and histological tests suggest they can be used in chronic studies. |