| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 봄 (04/11 ~ 04/12, 대전컨벤션센터) |
| 권호 |
38권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Surface functionalization of halloysite nanotubes by grafting of poly(poly(ethylene glycol) methacrylate) for bioactive interface via covalent immobilization of penicillin |
| 초록 |
A synthetic strategy for the functionalization of halloysite nanotubes (HNTs) by poly(poly(ethylene glycol) methacrylate) (PPEGMA) via surface-initiated atom transfer radical polymerization (SI-ATRP) allowing the covalent immobilization of antibiotics for the first time is developed. Multiamine polymer-functionalized HNTs were synthesized by controlled SI-ATRP of poly(ethylene glycol) methacrylate to form HNTs-g-PPEGMA, followed by silanization using (3-aminopropyl)trimethoxysilane to afford HNTs-g-PPEGMA-NH2 nanohybrids. Subsequently, penicillin was anchored on the surface of HNTs-g-PPEGMA-NH2 with multiamine groups on the external layers via the carbodiimide chemistry. The covalently attached penicillin retained their antibacterial activities against pathogens like Escherichia coli and Staphylococcus aureus. |
| 저자 |
Long Giang Bach, Md. Rafiqul Islam, 장명재, 김용훈, 임권택
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| 소속 |
부경대 |
| 키워드 |
halloysite nanotubes; poly(poly(ethylene glycol) methacrylate); ATRP; Antibacterial surface
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| E-Mail |
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