| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 가을 (10/09 ~ 10/10, 일산킨텍스) |
| 권호 |
33권 2호 |
| 발표분야 |
고분자 가공/복합재료 |
| 제목 |
Degradation of poly (ε-caprolactone) grafted dextran fibers and films in phosphate buffered saline |
| 초록 |
In this study poly(ε-caprolactone)grafted dextran(PGD) nanofibers and films were prepared from high molecular weight PGD by electrospinning and solvent evaporation,respectively.For both the cases,increase in the crystalline temperature(Tc) and heat of fusion was detected;this indicated that preferential hydrolytic degradation in the amorphous regions occurred followed by cleavage-induced crystallization.During the progress of hydrolysis,GPC chromatograms appeared bimodal for fibers and bi and tri-modal for the films. After 150 days of degradation,the pH was steady at 5.8 ± 0.3 for fibers and 6.1 ± 0.3 for films.This is mainly because of the morphological difference between fibers and films.The thicker film favors more autocatalysis then the fiber.Also the physical and molecular weight loss was faster in cases of films.This study suggests the application potential of PGD matrices in the fields of tissue engineering. |
| 저자 |
Madhab Prasad Bajgai1, 김학용2, 다만3, 강효경4, 고정안5, 길명섭1
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| 소속 |
1전북대, 23Department of Textile Engineering, 3Chonbuk National Univ., 4Chonju 561-756, 5Republic of Korea |
| 키워드 |
Biodegradable; matrix; amorphous; crystallization
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| E-Mail |
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