| 초록 |
Living cells are exposed to complex and functional microenvironment including soluble macromolecules, biophysical cues, and interactions between cell-cell and cell-extracellular matrix (ECM). In this talk, I will present multidisciplinary efforts directed towards the development of multiscale engineered biomimetic systems for biomedical applications. Specifically, I will talk about i) our current efforts on developing a series of advanced multiscale patterned platforms inspired by the unique architectures of native tissues and ECMs that can provide cells the in vivo-like topographical stem cell environment, and ii) their applications for better understanding of the function of living stem cells and tissue regeneration without complex surgical treatments or tissue transplantation in combination with traditional molecular and cell biology approaches. |
