| 학회 |
한국공업화학회 |
| 학술대회 |
2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
26권 1호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Magnetic Nanotransducers Induces Cancer Cell Death through Magneto Mitochondrial Dysfunction |
| 초록 |
Mitochondria play a critical role in cancer cells' intrinsic death mechanism. The remarkable vulnerability of cancer cells to mitochondrial dysfunction enables the development of novel therapeutic strategies. Magnetic nano-transducers are used to kill cancer cells remotely by inducing mitochondrial malfunction. To increase cellular internalization and magnetic transmission, spindle-shaped iron oxide nanoparticles were produced. By stimulating a mitochondrial quality control process called mitophagy, magneto-mechanical transduction of nanotransducers in mitochondria increases cancer cell death. |
| 저자 |
신하은, 한준혁, 박우람
|
| 소속 |
성균관대 |
| 키워드 |
Nanoparticle; Mitochondria; Nano-transducer; Cancer; Image-guided therapy
|
| E-Mail |
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