| 학회 |
한국공업화학회 |
| 학술대회 |
2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
26권 1호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Rapid Probe-Set Modification for Multiplex Biomolecule Detection via Direct Streptavidin Conjugation to Encoded Hydrogel Microparticles |
| 초록 |
Encoded hydrogel microparticles are superior tools for multiplex biomarker detections. However, the current method can not achieve a flexible probe-set modification, which is necessary for various combinations of target panels. Here, we present a simple method to conjugate streptavidin to the hydrogel particles for better assay performance and rapid probe-set modification. Streptavidin was conjugated to the encoded hydrogel microparticles using the simple click reaction. A highly flexible and sensitive assay was developed to quantify DNA and proteins using the presented methods. |
| 저자 |
장우경, 노윤호, 김주연, 문석준, 이혜선, 황창현, 박경화, 봉기완
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| 소속 |
고려대 |
| 키워드 |
hydrogels; probe-set modification; streptavidin; biomarker
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| E-Mail |
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